N-methyl d-aspartate receptor hypofunction reduces visual contextual integration
نویسندگان
چکیده
منابع مشابه
Combined Therapy for Anti-N-methyl D-aspartate Receptor Encephalitis
Background Anti-N-methyl- d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune neurological disorder that usually occurs as a paraneoplastic syndrome and is particularly associated with ovarian teratoma. Standard therapy for severe cases is not established and the prognosis in patients who do not respond to first-line treatment is poor. Case Report An 11-year-old boy complained ps...
متن کاملIntegration of contextual cues into memory depends on "prefrontal" N-methyl-D-aspartate receptors.
Every learning event is embedded in a context, but not always does the context become an integral part of the memory; however, for extinction learning it usually does, resulting in context-specific conditioned responding. The neuronal mechanisms underlying contextual control have been mainly investigated for Pavlovian fear extinction with a focus on hippocampal structures. However, the initial ...
متن کاملCompetitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats.
BACKGROUND AND PURPOSE We tested the hypothesis that administration of the competitive N-methyl-D-aspartate (NMDA) receptor antagonist NPC 17742 (2R,4R,5S-[2-amino-4,5-(1,2-cyclohexyl)-7-phosphonoheptanoic acid]) during transient focal ischemia affects early postischemic brain injury. METHODS Halothane-anesthetized cats underwent 1 hour of left middle cerebral artery occlusion plus 4 hours of...
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In this issue of Molecular Pharmacology, Low et al. (2003) delve into the mechanisms by which pH modulates the glutamate receptor subtype specifically activated by N–methylD-aspartate (NMDA). Based on a combination of scanning mutagenesis, patch clamp physiology, and molecular modeling, the authors conclude that amino acids involved in NMDA receptor modulation by protons are clustered in region...
متن کاملPediatric anti-N methyl D aspartate receptor encephalitis
Anti-N Methyl D Aspartate Receptor encephalitis (anti-NMDARE) is a recently defined disease, which is probably more under-recognized than rare. We report a case of anti-NMDARE in a 13-years-old girl, who presented with intractable seizures. To the best of our knowledge, this is the second case of pediatric anti-NMDARE being reported from India. The need for a greater awareness of this disease a...
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ژورنال
عنوان ژورنال: Journal of Vision
سال: 2021
ISSN: 1534-7362
DOI: 10.1167/jov.21.6.9